CUSHING'S SYNDROME IN CHILDHOOD, ADOLESCENCE, AND YOUNG ADULTHOOD: A RETROSPECTIVE ANALYSIS

Urmanova Yu. M.; Khamraeva Yu. S.; Pankiv V. A.; Tashmanova A. B.; Mavlonov U. Kh.; Savchuk D. V.

Authors

Urmanova Yu. M. Alfraganus University, Department of Internal Medicine Republic of Uzbekistan, Tashkent, 100190, Y. Karakamysh St. 2A
Khamraeva Yu. S. Alfraganus University, Department of Internal Medicine Republic of Uzbekistan, Tashkent, 100190, Y. Karakamysh St. 2A
Pankiv V. A. Ukrainian Scientific and Practical Center of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues, Ministry of Health of Ukraine Ukraine, Kyiv, Kharkiv Highway 121
Tashmanova A. B. Kazakh National Medical University named after S. D. Asfendiyarov, Department of Endocrinology Republic of Kazakhstan, 050012, Almaty, Tole bi street, 94
Mavlonov U. Kh. Bukhara branch of the Republican Specialized Scientific and Practical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after Academician Ya.Kh. Turakulov (200118, Bukhara region, Bukhara,Fathabad Street, 10
Savchuk D. V. Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after Academician Ya.Kh. Turakulov (Republic of Uzbekistan, Tashkent, 100125, Mirzo Ulugbek St. 56).

Keywords:

Cushing's syndrome and disease, hypercorticism, adolescents, course characteristics.

Abstract

In this article, the authors present literature data on the frequency and structure of causes of hypercorticism in children and adolescents. Based on the analysis of retrospective clinical data for 10 years, it was found that among patients with various forms of hypercorticism in this age period, patients with Itsenko-Cushing's disease predominated - 26 patients (66.6%), that is, with pituitary microadenomas, compared with patients with Itsenko-Cushing's syndrome - 4 (10.2%) and other forms of hypercorticism: juvenile dyspituitarism (JD) - 7 (17.9%), obesity with ACTH/cortisol secretion rhythm disorder - 1 (2.5%) and iatrogenic hypercorticism - 1 (2.5%).