American Journal of Interdisciplinary Research and Development

WAYS TO DEVELOP THE GREEN ECONOMY AND GREEN JOBS

Begimkulova Gulhayo Bakhtiyorovna — 2024-11-08

This article covers in detail the economic models that use natural resources wisely and protect the environment and aim to achieve social well-being, as well as the professions that operate in the areas of the green economy and contribute to sustainable development.

LINGUISTIC AND SOCIO-HUMANITARIAN ISSUES OF PERSONNEL TRAINING AND EDUCATION ORGANIZATION BASED ON DIGITAL TECHNOLOGIES AND INNOVATIVE APPROACH

Safarova Nargiza Bobomurodovna — 2024-11-09

In this article, in accordance with the decision of the President of the Republic of Uzbekistan on measures to create conditions for the rapid introduction of artificial intelligence technologies, the rapid introduction of artificial intelligence technologies and the development of a highly qualified staffing system in this field Information about the capture is given. In the article, the importance of the developing digital technologies and innovative approach in making the educational process more qualitative and effective, the importance of the development of the educational system based on modern technologies, comments on the role of digital educational resources and their transfer to the educational process. The given article mainly shows digital technologies in the field of education and their importance in making the educational process more effective and interesting. Also, the importance of paying attention to these areas in the process of personnel training and education is shown.

REGARDING THE WORK DONE IN THE AREA OF OVERSEEING THE ENFORCEMENT OF LEGISLATION RELATED TO THE PROTECTION OF ATMOSPHERIC AIR

K.T. Almatov — 2024-11-12

The article describes the problem of air pollution in cities, including the types of atmospheric pollution and methods to minimize their negative impacts.

ACTIVITY OF WOMEN IN SCIENCE, ADVANCED FOREIGN EXPERIENCES

Khurshida Tokhirovna Komilova — 2024-11-16

The article analyzes the activities of women and girls in the fields of science, and highlights the ideas of the advanced research of women scientists around the world. The contribution of women to science, the results of the analysis of the activities of women in various fields of science are highlighted. The role of education and science in the life of women in the field of science, its influence on socialization, and the social image of women in the field of science are highlighted. The activity of women in the fields of science is disclosed.

ESTABLISHMENT OF FARMS IN THE REPUBLIC OF UZBEKISTAN

Sanjarbek Khamrajonovich Mamajonov — 2024-11-16

The article provides a scientific analysis of the establishment of farm activity in the Republic of Uzbekistan during the years of independence, the reforms implemented by the government in the first and second stages of its development and their results on the basis of literature and archival sources.

THE CHANGES REGARDING THE SUPPLY OF SPECIALIST PERSONNEL TO THE FERGHANA VALLEY MEDICINE

Guldona Anvarbekovna Mamasolieva — 2024-11-16

In this article, the training of qualified medical personnel in the field of health care in Andizhan, Ferghana and Namangan regions of the Ferghana Valley, the work carried out in universities and secondary medical educational institutions in this direction, the activities of doctors and medical staff are studied with the help of scientific literature and archival data.

REACTIVE ARTHRITIS: LITERATURE REVIEW, TARGET TREATMENTS IN THE ERA OF BIOLOGICS

Javohir Mullokulov — 2024-11-16

Reactive arthritis (ReA) is an autoimmune condition characterized by joint inflammation that typically arises following an infection, most commonly in the gastrointestinal or genitourinary tract. It is considered part of the broader spectrum of spondyloarthropathies, with hallmark symptoms including asymmetric arthritis, enthesitis, and dactylitis, often involving the lower limbs. The condition is triggered by bacterial infections, such as Chlamydia trachomatis, Salmonella, or Campylobacter, although the exact pathogenic mechanisms remain unclear. Reactive arthritis may manifest as acute, self-limiting inflammation, or progress to a chronic condition, leading to prolonged disability and joint damage in severe cases.[1]. This review explores the clinical presentation, pathophysiology, diagnostic criteria, and treatment strategies for ReA. Therapeutic interventions range from nonsteroidal anti-inflammatory drugs (NSAIDs) for pain management to disease-modifying antirheumatic drugs (DMARDs) and biologic agents like TNF inhibitors for persistent and severe cases. Recent advances in understanding the molecular mechanisms, particularly the role of HLA-B27 and cytokine dysregulation, offer new insights into potential therapeutic targets. Early diagnosis and appropriate management are crucial for preventing long-term complications and improving patient outcomes. This article also discusses emerging treatments and the challenges of managing ReA in the context of coexisting infections and chronic disease.[2].

DIAGNOSTIC VALUE OF ADAMTS-7 IN JOINT DISEASES

Feruza Iskandarovna Khalmetova — 2024-11-16

Reactive arthritis (RеА) is a "sterile" inflammatory joint disease in which infectious agents and their antigens are absent in the synovial fluid and synovial membrane of patients. RеА is a seronegative spondyloarthritis, which meets the criteria of the European Group for the Study of Spondyloarthritis. With the introduction into clinical practice in the early 90s of the reverse transcriptase polymerase chain reaction (RT–PCR) method, small amounts of Ch.trachomatis DNA and RNA were found in the joint cavity. The presence of these nucleic acids, which have a very short lifetime in tissues (several minutes), indicated the possibility of transcription and, consequently, active reproduction of bacteria in the joint cavity.

THE ROLE OF THE SYSTEM OF TUTORING IN HIGHER EDUCATION AND THE IMPORTANCE OF STUDENTS IN THE PROCESS OF OBTAINING EDUCATION

Nurmatova Madina Odiljon — 2024-11-17

The current education system is constantly updated and seeks to provide quality education for students. Of particular importance in this process is the system of tutoring, that is, mentoring. This article will consider in detail and problems of the role, benefits, impact on students in modern education.

ARTISTIC INTERPRETATION OF THE IMAGE OF THE WRITER – JADIDA

Mansurova Malika Askarovna — 2024-11-19

This article analyzes the story “Flower of Hope” by the famous Uzbek writer Khurshid Dostmuhammad, the author focuses on the specificity of creating the image of Fitrat, as well as the author's skill in creating the image of the writer. The article also examines the role of historical sources in creating the image of the main character, and the interpretations that the writer was guided by.

ANALYSIS OF MODERN RISK FACTORS CONTRIBUTING TO THE DEVELOPMENT OF ATHEROSCLEROSIS

Don A. N. — 2024-11-20

This literature review discusses modern risk factors contributing to the development of atherosclerosis, one of the most significant healthcare issues today. The results of experimental and clinical studies are analyzed, and their findings are discussed in the context of existing knowledge. Special attention is given to data obtained from male ApoE-deficient mice, where it has been established that the glucagon-like peptide-1 receptor agonist, Exenatide-4, improves atherosclerosis by activating the secretion of myeloid suppressor cells in the bone marrow and peripheral blood. Additionally, other factors are considered, such as apolipoprotein L1 and the consequences of brain ischemia, leading to sustained activation and increased regulation of adhesion molecules like VCAM1. The increase in aging of peripheral endothelial cells observed up to 4 weeks post-stroke and the prevalence of atherosclerosis in the carotid arteries in elderly individuals is also discussed. The work emphasizes the use of single-cell RNA sequencing (scRNA-seq) as a method for studying atherosclerosis progression. Furthermore, questions are raised about the influence of dietary traditions and comorbid conditions, such as the combination of atherosclerosis with diabetes and thyroid diseases.

ADMINISTRATIVE PRACTICES OF THE KHWARAZM EMPIRE: LESSONS FOR MODERN GOVERNANCE

Kalandarov Bilolkhon Jalolkhon ugli — 2024-11-21

The administrative system of the Khwarazm Empire, which thrived between the 11th and 13th centuries, offers valuable insights into governance that can be adapted for modern administration. This article explores the administrative practices of the Khwarazm Empire, focusing on its centralized bureaucracy, regional governance, tax system, and its innovative approach to public order and legal administration. By analyzing these practices, this paper seeks to identify key lessons for contemporary governance, particularly in terms of state-building, resource management, and conflict resolution.

FUNDAMENTALS OF MODERN APPROACH TO TEACHING UZBEK NATIONAL MUSICAL ART

Turdiyev Shavkat Akhmedovich — 2024-11-21

This scientific article analyzes the foundations of modern approaches to the teaching of Uzbek national musical art. The article examines the importance of active teaching methods, modern technologies and individual approaches in the educational process. Information is provided about the activities carried out in order to introduce new pedagogical approaches to teaching the rich heritage of Uzbek national musical art, to develop student creativity and preserve cultural heritage. The article contains important recommendations to make the process of teaching Uzbek national music more effective and interesting.